Clinical Trials & Research

Sertraline, an antidepressant that doctors commonly prescribe, appears to work by reducing anxiety first and doesn’t start tackling depressive symptoms until weeks later. New research sheds fresh light on how antidepressants work. This was the main finding of a study on the use of antidepressants in primary care settings in the United Kingdom. The researchers
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Researchers from the United Kingdom have appraised the most recent assessment by the European Food Safety Authority regarding the safety of aspartame, a popular type of artificial sweetener. The investigators caution that the commission’s findings may be misleading. Is aspartame really as safe as official reports claim? Some researchers are unsure. Aspartame is perhaps the
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A new drug for treating Alzheimer’s disease has successfully passed the first phase of testing in humans. Preclinical studies had already shown that the drug could improve memory and other symptoms of Alzheimer’s disease in older mice. A potential treatment for Alzheimer’s moves a step closer. Researchers at Forschungszentrum Jülich and Heinrich Heine University Düsseldorf,
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Laboratory and animal studies have suggested that the leukemia drug nilotinib could alleviate symptoms of Parkinson’s disease. Now, using early results from a clinical trial in humans, scientists have worked out how the drug reduces toxic protein and raises dopamine levels in the brain. New research explains how a cancer drug increases levels of the
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A series of clinical trials have tested an experimental treatment for Parkinson’s disease that uses a novel approach: administering the drug straight into the brain via implanted ports. The leading researchers believe this may be a “breakthrough” therapeutic strategy for neurological conditions. Newly trialed therapy could launch a fresh chapter in the treatment of Parkinson’s
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For the first time in decades, researchers have identified a new medication that can successfully treat major depression. An existing oral drug may relieve major depression. Depression affects about 300 million people across the globe, making the condition the “leading cause of ill health and disability worldwide,” according to the World Health Organization (WHO). In
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New research has revealed that targeted cognitive training can successfully reduce cognitive impairment in treatment-resistant schizophrenia. Altering certain neural pathways may improve cognitive ability in people with treatment-resistant schizophrenia. Schizophrenia is one of the 15 leading causes of disability globally. In the United States, this condition affects more than 3 million people. Symptoms of schizophrenia
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A preliminary clinical trial shows that stem cell transplantation, along with a tolerable dose of chemotherapy, is safe and more effective at slowing down multiple sclerosis than other existing therapies. Scientists were able to slow down MS progression in a new clinical trial using stem cell transplantation. Multiple sclerosis (MS) is a chronic neurodegenerative condition
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